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Novel Convenient Approach to the Solid-Phase Synthesis of Oligonucleotide Conjugates
A novel and convenient approach for the solid-phase 5′-functionalization of oligonucleotides is proposed in this article. The approach is based on the activation of free 5′-hydroxyl of polymer support-bound protected oligonucleotides by N,N′-disuccinimidyl carbonate followed by interaction with amin...
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| Pubblicato in: | Molecules |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6930482/ https://ncbi.nlm.nih.gov/pubmed/31771111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24234266 |
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