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DEEPSEN: a convolutional neural network based method for super-enhancer prediction

BACKGROUND: Super-enhancers (SEs) are clusters of transcriptional active enhancers, which dictate the expression of genes defining cell identity and play an important role in the development and progression of tumors and other diseases. Many key cancer oncogenes are driven by super-enhancers, and th...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Bu, Hongda, Hao, Jiaqi, Gan, Yanglan, Zhou, Shuigeng, Guan, Jihong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929276/
https://ncbi.nlm.nih.gov/pubmed/31874597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3180-z
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