DEEPSEN: a convolutional neural network based method for super-enhancer prediction

BACKGROUND: Super-enhancers (SEs) are clusters of transcriptional active enhancers, which dictate the expression of genes defining cell identity and play an important role in the development and progression of tumors and other diseases. Many key cancer oncogenes are driven by super-enhancers, and th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Bioinformatics
Prif Awduron: Bu, Hongda, Hao, Jiaqi, Gan, Yanglan, Zhou, Shuigeng, Guan, Jihong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929276/
https://ncbi.nlm.nih.gov/pubmed/31874597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3180-z
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