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DEEPSEN: a convolutional neural network based method for super-enhancer prediction

BACKGROUND: Super-enhancers (SEs) are clusters of transcriptional active enhancers, which dictate the expression of genes defining cell identity and play an important role in the development and progression of tumors and other diseases. Many key cancer oncogenes are driven by super-enhancers, and th...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Bu, Hongda, Hao, Jiaqi, Gan, Yanglan, Zhou, Shuigeng, Guan, Jihong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929276/
https://ncbi.nlm.nih.gov/pubmed/31874597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3180-z
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