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DEEPSEN: a convolutional neural network based method for super-enhancer prediction

BACKGROUND: Super-enhancers (SEs) are clusters of transcriptional active enhancers, which dictate the expression of genes defining cell identity and play an important role in the development and progression of tumors and other diseases. Many key cancer oncogenes are driven by super-enhancers, and th...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Bu, Hongda, Hao, Jiaqi, Gan, Yanglan, Zhou, Shuigeng, Guan, Jihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6929276/
https://ncbi.nlm.nih.gov/pubmed/31874597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3180-z
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