ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization

α-Synuclein (α-Syn) forms toxic intracellular protein inclusions and transmissible amyloid structures in Parkinson’s disease (PD). Preventing α-Syn self-assembly has become one of the most promising approaches in the search for disease-modifying treatments for this neurodegenerative disorder. Here,...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Peña-Díaz, Samuel, Pujols, Jordi, Conde-Giménez, María, Čarija, Anita, Dalfo, Esther, García, Jesús, Navarro, Susanna, Pinheiro, Francisca, Santos, Jaime, Salvatella, Xavier, Sancho, Javier, Ventura, Salvador
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928008/
https://ncbi.nlm.nih.gov/pubmed/31920537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00306
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