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Extracellular Vesicles From Pathological Microenvironment Induce Endothelial Cell Transformation and Abnormal Angiogenesis via Modulation of TRPV4 Channels

The soluble and mechanical microenvironment surrounding endothelial cells influences and instructs them to form new blood vessels. The cells in the pathological tumor microenvironment release extracellular vesicles (EVs) for paracrine signaling. EVs have been shown to induce angiogenesis by communic...

詳細記述

保存先:
書誌詳細
出版年:Front Cell Dev Biol
主要な著者: Guarino, Brianna D., Adapala, Ravi K., Kanugula, Anantha K., Lenkey, Nina M., Dougherty, Julie A., Paruchuri, Sailaja, Khan, Mahmood, Thodeti, Charles K.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928002/
https://ncbi.nlm.nih.gov/pubmed/31921855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00344
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