Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism

Reprogramming of adipocyte function in obesity is implicated in metabolic disorders like type 2 diabetes. Here, we used the pig, an animal model sharing many physiological and pathophysiological similarities with humans, to perform in-depth epigenomic and transcriptomic characterization of pure adip...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Jacobsen, Mette Juul, Havgaard, Jakob H., Anthon, Christian, Mentzel, Caroline M. Junker, Cirera, Susanna, Krogh, Poula Maltha, Pundhir, Sachin, Karlskov-Mortensen, Peter, Bruun, Camilla S., Lesnik, Philippe, Guerin, Maryse, Gorodkin, Jan, Jørgensen, Claus B., Fredholm, Merete, Barrès, Romain
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927937/
https://ncbi.nlm.nih.gov/pubmed/31921306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01268
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