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Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels

Dyslipidemia is the primary cause of cardiovascular disease, which is a serious human health problem in large parts of the world. Therefore, it is important to understand the genetic and molecular mechanisms that regulate blood levels of cholesterol and other lipids. Discovery of genetic elements in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Qianqian, Cai, Zexi, Lhomme, Marie, Sahana, Goutam, Lesnik, Philippe, Guerin, Maryse, Fredholm, Merete, Karlskov-Mortensen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595098/
https://ncbi.nlm.nih.gov/pubmed/33116219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75612-6
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