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Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels

Dyslipidemia is the primary cause of cardiovascular disease, which is a serious human health problem in large parts of the world. Therefore, it is important to understand the genetic and molecular mechanisms that regulate blood levels of cholesterol and other lipids. Discovery of genetic elements in...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Zhang, Qianqian, Cai, Zexi, Lhomme, Marie, Sahana, Goutam, Lesnik, Philippe, Guerin, Maryse, Fredholm, Merete, Karlskov-Mortensen, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595098/
https://ncbi.nlm.nih.gov/pubmed/33116219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75612-6
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