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Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels

Dyslipidemia is the primary cause of cardiovascular disease, which is a serious human health problem in large parts of the world. Therefore, it is important to understand the genetic and molecular mechanisms that regulate blood levels of cholesterol and other lipids. Discovery of genetic elements in...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Zhang, Qianqian, Cai, Zexi, Lhomme, Marie, Sahana, Goutam, Lesnik, Philippe, Guerin, Maryse, Fredholm, Merete, Karlskov-Mortensen, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595098/
https://ncbi.nlm.nih.gov/pubmed/33116219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75612-6
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