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Octadecyloxyethyl benzyl tenofovir: A novel tenofovir diester provides sustained intracellular levels of tenofovir diphosphate

Pre-exposure prophylaxis (PrEP) with topically or systemically administered antiretroviral agents can prevent acquisition of human immunodeficiency virus type 1 (HIV-1) infection. However, in clinical trials using tenofovir-containing agents, HIV-1 acquisition is reduced but not eliminated. Incomple...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Beadle, James R., Aldern, Kathy A., Zhang, Xing-Quan, Valiaeva, Nadejda, Hostetler, Karl Y., Schooley, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927535/
https://ncbi.nlm.nih.gov/pubmed/31550449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.104614
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