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Complete stereoinversion of l-tryptophan by a fungal single-module nonribosomal peptide synthetase

Single-module nonribosomal peptide synthetases (NRPSs) and NRPS-like enzymes activate and transform carboxylic acids in both primary and secondary metabolism; and are of great interests due to their biocatalytic potentials. The single-module NRPS IvoA is essential for fungal pigment biosynthesis. He...

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Pubblicato in:J Am Chem Soc
Autori principali: Hai, Yang, Jenner, Matthew, Tang, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927398/
https://ncbi.nlm.nih.gov/pubmed/31573806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b08898
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