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A Fungal Nonribosomal Peptide Synthetase Module that can Synthesize Thiopyrazines
[Image: see text] A nonribosomal peptide synthetase-like enzyme (NRPS325) from Aspergillus terreus was reconstituted in vitro and was shown to synthesize thiopyrazines using an unprecedented mechanism. Substrate promiscuity of NRPS325 towards different amino acids and free thiols was explored to pro...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064727/ https://ncbi.nlm.nih.gov/pubmed/21384820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200288w |
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