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Decoding and reprogramming fungal iterative nonribosomal peptide synthetases

Nonribosomal peptide synthetases (NRPSs) assemble a large group of structurally and functionally diverse natural products. While the iterative catalytic mechanism of bacterial NRPSs is known, it remains unclear how fungal NRPSs create products of desired length. Here we show that fungal iterative NR...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Yu, Dayu, Xu, Fuchao, Zhang, Shuwei, Zhan, Jixun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457498/
https://ncbi.nlm.nih.gov/pubmed/28534477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15349
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