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Decoding and reprogramming fungal iterative nonribosomal peptide synthetases

Nonribosomal peptide synthetases (NRPSs) assemble a large group of structurally and functionally diverse natural products. While the iterative catalytic mechanism of bacterial NRPSs is known, it remains unclear how fungal NRPSs create products of desired length. Here we show that fungal iterative NR...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yu, Dayu, Xu, Fuchao, Zhang, Shuwei, Zhan, Jixun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457498/
https://ncbi.nlm.nih.gov/pubmed/28534477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15349
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