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Module evolution and substrate specificity of fungal nonribosomal peptide synthetases involved in siderophore biosynthesis

BACKGROUND: Most filamentous ascomycete fungi produce high affinity iron chelators called siderophores, biosynthesized nonribosomally by multimodular adenylating enzymes called nonribosomal peptide synthetases (NRPSs). While genes encoding the majority of NRPSs are intermittently distributed across...

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Bibliographic Details
Main Authors: Bushley, Kathryn E, Ripoll, Daniel R, Turgeon, B Gillian
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644324/
https://ncbi.nlm.nih.gov/pubmed/19055762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-328
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