Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival

PURPOSE: Neuroendocrine differentiation of prostate cancer, induced by androgen deprivation therapy, is mainly related to advanced disease and poor clinical outcome. Genetic and epigenetic alterations are the key elements of the prostate carcinogenesis. A group of compounds able to induce changes in...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Giordano, Francesca, Naimo, Giuseppina Daniela, Nigro, Alessandra, Romeo, Francesco, Paolì, Alessandro, De Amicis, Francesca, Vivacqua, Adele, Morelli, Catia, Mauro, Loredana, Panno, Maria Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927225/
https://ncbi.nlm.nih.gov/pubmed/31908413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S229930
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