Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival

PURPOSE: Neuroendocrine differentiation of prostate cancer, induced by androgen deprivation therapy, is mainly related to advanced disease and poor clinical outcome. Genetic and epigenetic alterations are the key elements of the prostate carcinogenesis. A group of compounds able to induce changes in...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Giordano, Francesca, Naimo, Giuseppina Daniela, Nigro, Alessandra, Romeo, Francesco, Paolì, Alessandro, De Amicis, Francesca, Vivacqua, Adele, Morelli, Catia, Mauro, Loredana, Panno, Maria Luisa
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927225/
https://ncbi.nlm.nih.gov/pubmed/31908413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S229930
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