Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival

PURPOSE: Neuroendocrine differentiation of prostate cancer, induced by androgen deprivation therapy, is mainly related to advanced disease and poor clinical outcome. Genetic and epigenetic alterations are the key elements of the prostate carcinogenesis. A group of compounds able to induce changes in...

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Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Giordano, Francesca, Naimo, Giuseppina Daniela, Nigro, Alessandra, Romeo, Francesco, Paolì, Alessandro, De Amicis, Francesca, Vivacqua, Adele, Morelli, Catia, Mauro, Loredana, Panno, Maria Luisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927225/
https://ncbi.nlm.nih.gov/pubmed/31908413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S229930
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