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How do DNA-bound proteins leave their binding sites? The role of facilitated dissociation
Dissociation of a protein from DNA is often assumed to be described by an off rate that is independent of other molecules in solution. Recent experiments and computational analyses have challenged this view by showing that unbinding rates (residence times) of DNA-bound proteins can depend on concent...
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| Udgivet i: | Curr Opin Chem Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926143/ https://ncbi.nlm.nih.gov/pubmed/31586479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2019.08.007 |
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