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Facilitated dissociation of transcription factors from single DNA binding sites

The binding of transcription factors (TFs) to DNA controls most aspects of cellular function, making the understanding of their binding kinetics imperative. The standard description of bimolecular interactions posits that TF off rates are independent of TF concentration in solution. However, recent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kamar, Ramsey I., Banigan, Edward J., Erbas, Aykut, Giuntoli, Rebecca D., Olvera de la Cruz, Monica, Johnson, Reid C., Marko, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402408/
https://ncbi.nlm.nih.gov/pubmed/28364020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701884114
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