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β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward

Evidence shows that the neurotransmitter dopamine mediates the rewarding effects of nicotine and other drugs of abuse, while nondopaminergic neural substrates mediate the negative motivational effects. β2* nicotinic acetylcholine receptors (nAChR) are necessary and sufficient for the experience of b...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Grieder, Taryn E., Besson, Morgane, Maal-Bared, Geith, Pons, Stéphanie, Maskos, Uwe, van der Kooy, Derek
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925992/
https://ncbi.nlm.nih.gov/pubmed/31776253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908724116
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