Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitizes locomotor responding to the drug

Dopaminergic projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAcc) mediate the behavioral and motivational effects of many drugs of abuse, including nicotine. Repeated intermittent administration of these drugs, a pattern often associated with initial drug exposure, sensi...

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Detalhes bibliográficos
Main Authors: Baker, Lorinda K, Mao, Danyan, Chi, Henry, Govind, Anitha P, Vallejo, Yolanda F, Iacoviello, Michael, Herrera, Stacy, Cortright, James J, Green, William N, McGehee, Daniel S, Vezina, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604051/
https://ncbi.nlm.nih.gov/pubmed/23331514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12114
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