Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitizes locomotor responding to the drug

Dopaminergic projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAcc) mediate the behavioral and motivational effects of many drugs of abuse, including nicotine. Repeated intermittent administration of these drugs, a pattern often associated with initial drug exposure, sensi...

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Hlavní autoři: Baker, Lorinda K, Mao, Danyan, Chi, Henry, Govind, Anitha P, Vallejo, Yolanda F, Iacoviello, Michael, Herrera, Stacy, Cortright, James J, Green, William N, McGehee, Daniel S, Vezina, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604051/
https://ncbi.nlm.nih.gov/pubmed/23331514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12114
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