Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitizes locomotor responding to the drug

Dopaminergic projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAcc) mediate the behavioral and motivational effects of many drugs of abuse, including nicotine. Repeated intermittent administration of these drugs, a pattern often associated with initial drug exposure, sensi...

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Main Authors: Baker, Lorinda K, Mao, Danyan, Chi, Henry, Govind, Anitha P, Vallejo, Yolanda F, Iacoviello, Michael, Herrera, Stacy, Cortright, James J, Green, William N, McGehee, Daniel S, Vezina, Paul
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604051/
https://ncbi.nlm.nih.gov/pubmed/23331514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12114
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