Gene therapy-emulating small molecule treatments in cystic fibrosis airway epithelial cells and patients

BACKGROUND: Several small molecule corrector and potentiator drugs have recently been licensed for Cystic Fibrosis (CF) therapy. However, other aspects of the disease, especially inflammation, are less effectively treated by these drugs. We hypothesized that small molecule drugs could function eithe...

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Vydáno v:Respir Res
Hlavní autoři: Yang, Q., Soltis, A. R., Sukumar, G., Zhang, X., Caohuy, H., Freedy, J., Dalgard, C. L., Wilkerson, M. D., Pollard, H. B., Pollard, B. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925517/
https://ncbi.nlm.nih.gov/pubmed/31864360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1214-8
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