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Gene therapy-emulating small molecule treatments in cystic fibrosis airway epithelial cells and patients

BACKGROUND: Several small molecule corrector and potentiator drugs have recently been licensed for Cystic Fibrosis (CF) therapy. However, other aspects of the disease, especially inflammation, are less effectively treated by these drugs. We hypothesized that small molecule drugs could function eithe...

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Pubblicato in:Respir Res
Autori principali: Yang, Q., Soltis, A. R., Sukumar, G., Zhang, X., Caohuy, H., Freedy, J., Dalgard, C. L., Wilkerson, M. D., Pollard, H. B., Pollard, B. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925517/
https://ncbi.nlm.nih.gov/pubmed/31864360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1214-8
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