Small Molecule Anion Carriers Correct Abnormal Airway Surface Liquid Properties in Cystic Fibrosis Airway Epithelia

Cystic fibrosis (CF) is a genetic disease characterized by the lack of cystic fibrosis transmembrane conductance regulator (CFTR) protein expressed in epithelial cells. The resulting defective chloride and bicarbonate secretion and imbalance of the transepithelial homeostasis lead to abnormal airway...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Gianotti, Ambra, Capurro, Valeria, Delpiano, Livia, Mielczarek, Marcin, García-Valverde, María, Carreira-Barral, Israel, Ludovico, Alessandra, Fiore, Michele, Baroni, Debora, Moran, Oscar, Quesada, Roberto, Caci, Emanuela
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073096/
https://ncbi.nlm.nih.gov/pubmed/32098269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041488
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