Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy

Cystic fibrosis (CF) is a genetic lethal disease, originated from the defective function of the CFTR protein, a chloride and bicarbonate permeable transmembrane channel. CF mutations affect CFTR protein through a variety of molecular mechanisms which result in different functional defects. Current t...

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Udgivet i:Front Pharmacol
Main Authors: Cossu, Claudia, Fiore, Michele, Baroni, Debora, Capurro, Valeria, Caci, Emanuela, Garcia-Valverde, Maria, Quesada, Roberto, Moran, Oscar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090297/
https://ncbi.nlm.nih.gov/pubmed/30131695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00852
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