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Small molecule anionophores promote transmembrane anion permeation matching CFTR activity

Anion selective ionophores, anionophores, are small molecules capable of facilitating the transmembrane transport of anions. Inspired in the structure of natural product prodigiosin, four novel anionophores 1a-d, including a 1,2,3-triazole group, were prepared. These compounds proved highly efficien...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Hernando, Elsa, Capurro, Valeria, Cossu, Claudia, Fiore, Michele, García-Valverde, María, Soto-Cerrato, Vanessa, Pérez-Tomás, Ricardo, Moran, Oscar, Zegarra-Moran, Olga, Quesada, Roberto
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805763/
https://ncbi.nlm.nih.gov/pubmed/29422673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20708-3
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