Small molecule‐facilitated anion transporters in cells for a novel therapeutic approach to cystic fibrosis

BACKGROUND AND PURPOSE: Cystic fibrosis (CF) is a lethal autosomal recessive genetic disease that originates from the defective function of the CF transmembrane conductance regulator (CFTR) protein, a cAMP‐dependent anion channel involved in fluid transport across epithelium. Because small synthetic...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Fiore, Michele, Cossu, Claudia, Capurro, Valeria, Picco, Cristiana, Ludovico, Alessandra, Mielczarek, Marcin, Carreira‐Barral, Israel, Caci, Emanuela, Baroni, Debora, Quesada, Roberto, Moran, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514296/
https://ncbi.nlm.nih.gov/pubmed/30825185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14649
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