Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis

Radiation-induced lung injury (RILI) is one of the most common and fatal complications of thoracic radiotherapy, whereas no effective interventions are available. Andrographolide, an active component extracted from Andrographis paniculate, is prescribed as a treatment for upper respiratory tract inf...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gao, Jian, Peng, Shuang, Shan, Xinni, Deng, Guoliang, Shen, Lihong, Sun, Jian, Jiang, Chunhong, Yang, Xiaoling, Chang, Zhigang, Sun, Xinchen, Feng, Fude, Kong, Lingdong, Gu, Yanhong, Guo, Wenjie, Xu, Qiang, Sun, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925222/
https://ncbi.nlm.nih.gov/pubmed/31862870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2195-8
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