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AIM2 Inflammasome-Mediated Pyroptosis in Enterovirus A71-Infected Neuronal Cells Restricts Viral Replication

Encephalomyelitis is a well-known complication of hand, foot, and mouth disease (HFMD) due to Enterovirus 71 (EV71) infection. Viral RNA/antigens could be detected in the central nervous system (CNS) neurons in fatal encephalomyelitis but the mechanisms of neuronal cell death is not clearly understo...

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Publicat a:Sci Rep
Autors principals: Yogarajah, Thinesshwary, Ong, Kien Chai, Perera, David, Wong, Kum Thong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517550/
https://ncbi.nlm.nih.gov/pubmed/28724943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05589-2
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