Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

In this study, we attempted to explore the effect and possible mechanism of Andrographolide on OVA-induced asthma. OVA challenge induced significant airway inflammatory cell recruitment and lung histological alterations, which were ameliorated by Andrographolide. The protein levels of cytokines in b...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Peng, Shuang, Gao, Jian, Liu, Wen, Jiang, Chunhong, Yang, Xiaoling, Sun, Yang, Guo, Wenjie, Xu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348318/
https://ncbi.nlm.nih.gov/pubmed/27793052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12918
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