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Cytokine secretion and pyroptosis of cholesteatoma keratinocytes mediated by AIM2 inflammasomes in response to cytoplasmic DNA

Cholesteatoma constitutes an acquired benign epidermal non-permanent bone lesion that is locally destructive and patients often relapse. Inflammasomes, which mediate the maturation and production of IL-18 and IL-1β, resulting in pyroptosis, have been documented to serve a core function in multiple i...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zhang, Chen, Chen, Min, Chi, Zhangcai
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974272/
https://ncbi.nlm.nih.gov/pubmed/33760111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11983
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