The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine

We have recently demonstrated that purinergic signaling in bone marrow (BM) microenvironment regulates mobilization of hematopoietic stem progenitor cells (HSPCs), mesenchymal stroma cells (MSCs), endothelial progenitor cells (EPCs), and very small embryonic like stem cells (VSELs) into the peripher...

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Detalhes bibliográficos
Publicado no:Stem Cell Rev Rep
Main Authors: Adamiak, Mateusz, Bujko, Kamila, Brzezniakiewicz-Janus, Katarzyna, Kucia, Magda, Ratajczak, Janina, Ratajczak, Mariusz Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925070/
https://ncbi.nlm.nih.gov/pubmed/31520298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-019-09918-y
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