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Fungal Highly Reducing Polyketide Synthases Biosynthesize Salicylaldehydes that are Precursors to Epoxycyclohexenol Natural Products

Fungal highly reducing polyketide synthases (HRPKSs) are highly programmed multidomain enzymes that synthesize reduced polyketide structures. Recent reports indicated salicylaldehydes are synthesized by HRPKS biosynthetic gene clusters, which are unexpected based on known enzymology of HRPKSs. Using...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Liu, Ling, Tang, Man-Cheng, Tang, Yi
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924165/
https://ncbi.nlm.nih.gov/pubmed/31790246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09669
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