Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases

Fungal polyketide synthases (PKSs) can function collaboratively to synthesize natural products of significant structural diversity. Here we present a new mode of collaboration between a highly reducing PKS (HRPKS) and a PKS-nonribosomal peptide synthetase (PKS-NRPS) in the synthesis of oxaleimides f...

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Vydáno v:J Am Chem Soc
Hlavní autoři: Sato, Michio, Dander, Jacob E., Sato, Chizuru, Hung, Yiu-Sun, Gao, Shu-Shan, Tang, Man-Cheng, Hang, Leibniz, Winter, Jaclyn M., Garg, Neil K., Watanabe, Kenji, Tang, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673468/
https://ncbi.nlm.nih.gov/pubmed/28365998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02432
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