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Acyltransferase Mediated Polyketide Release from a Fungal Megasynthase
[Image: see text] LovF is a highly reducing polyketide synthase (HR-PKS) from the filamentous fungus Aspergillus terreus. LovF synthesizes the α-S-methylbutyrate side chain that is subsequently transferred to monacolin J to yield the cholesterol-lowering natural product lovastatin. In the report, we...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878198/ https://ncbi.nlm.nih.gov/pubmed/19530726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja903203g |
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