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Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis

Modular collaboration between iterative fungal polyketide synthases (IPKSs) is an important mechanism for generating structural diversity of polyketide natural products. Inter-PKS communication and substrate channeling are controlled in large by the starter unit acyl carrier protein transacylase (SA...

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Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Winter, Jaclyn M., Cascio, Duilio, Dietrich, David, Sato, Michio, Watanabe, Kenji, Sawaya, Michael R., Vederas, John C., Tang, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922798/
https://ncbi.nlm.nih.gov/pubmed/26172141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04520
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