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Fully moderated t-statistic in linear modeling of mixed effects for differential expression analysis
BACKGROUND: Gene expression profiling experiments with few replicates lead to great variability in the estimates of gene variances. Toward this end, several moderated t-test methods have been developed to reduce this variability and to increase power for testing differential expression. Most of thes...
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| Veröffentlicht in: | BMC Bioinformatics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923909/ https://ncbi.nlm.nih.gov/pubmed/31861977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3248-9 |
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