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Power analysis for RNA-Seq differential expression studies using generalized linear mixed effects models

BACKGROUND: Power analysis becomes an inevitable step in experimental design of current biomedical research. Complex designs allowing diverse correlation structures are commonly used in RNA-Seq experiments. However, the field currently lacks statistical methods to calculate sample size and estimate...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Yu, Lianbo, Fernandez, Soledad, Brock, Guy
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236949/
https://ncbi.nlm.nih.gov/pubmed/32429934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3541-7
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