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Power analysis for RNA-Seq differential expression studies using generalized linear mixed effects models

Abstract Background Power analysis becomes an inevitable step in experimental design of current biomedical research. Complex designs allowing diverse correlation structures are commonly used in RNA-Seq experiments. However, the field currently lacks statistical methods to calculate sample size and e...

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Hlavní autoři: Lianbo Yu, Soledad Fernandez, Guy Brock
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2020-05-01
Edice:BMC Bioinformatics
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On-line přístup:http://link.springer.com/article/10.1186/s12859-020-3541-7
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