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Power analysis for RNA-Seq differential expression studies using generalized linear mixed effects models

Abstract Background Power analysis becomes an inevitable step in experimental design of current biomedical research. Complex designs allowing diverse correlation structures are commonly used in RNA-Seq experiments. However, the field currently lacks statistical methods to calculate sample size and e...

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Bibliographische Detailangaben
Hauptverfasser: Lianbo Yu, Soledad Fernandez, Guy Brock
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-05-01
Schriftenreihe:BMC Bioinformatics
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Online Zugang:http://link.springer.com/article/10.1186/s12859-020-3541-7
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