Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform

Current approaches to reducing the latent HIV reservoir entail first reactivating virus-containing cells to become visible to the immune system. A critical second step is killing these cells to reduce reservoir size. Endogenous cytotoxic T-lymphocytes (CTLs) may not be adequate because of cellular e...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Herzig, Eytan, Kim, Kaman Chan, Packard, Thomas A., Vardi, Noam, Schwarzer, Roland, Gramatica, Andrea, Deeks, Steven G., Williams, Steven R., Landgraf, Kyle, Killeen, Nigel, Martin, David W., Weinberger, Leor S., Greene, Warner C.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922308/
https://ncbi.nlm.nih.gov/pubmed/31668804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.10.002
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