Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform

Current approaches to reducing the latent HIV reservoir entail first reactivating virus-containing cells to become visible to the immune system. A critical second step is killing these cells to reduce reservoir size. Endogenous cytotoxic T-lymphocytes (CTLs) may not be adequate because of cellular e...

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Vydáno v:Cell
Hlavní autoři: Herzig, Eytan, Kim, Kaman Chan, Packard, Thomas A., Vardi, Noam, Schwarzer, Roland, Gramatica, Andrea, Deeks, Steven G., Williams, Steven R., Landgraf, Kyle, Killeen, Nigel, Martin, David W., Weinberger, Leor S., Greene, Warner C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922308/
https://ncbi.nlm.nih.gov/pubmed/31668804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.10.002
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