Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform

Current approaches to reducing the latent HIV reservoir entail first reactivating virus-containing cells to become visible to the immune system. A critical second step is killing these cells to reduce reservoir size. Endogenous cytotoxic T-lymphocytes (CTLs) may not be adequate because of cellular e...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Herzig, Eytan, Kim, Kaman Chan, Packard, Thomas A., Vardi, Noam, Schwarzer, Roland, Gramatica, Andrea, Deeks, Steven G., Williams, Steven R., Landgraf, Kyle, Killeen, Nigel, Martin, David W., Weinberger, Leor S., Greene, Warner C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922308/
https://ncbi.nlm.nih.gov/pubmed/31668804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.10.002
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