Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform

Current approaches to reducing the latent HIV reservoir entail first reactivating virus-containing cells to become visible to the immune system. A critical second step is killing these cells to reduce reservoir size. Endogenous cytotoxic T-lymphocytes (CTLs) may not be adequate because of cellular e...

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Udgivet i:Cell
Main Authors: Herzig, Eytan, Kim, Kaman Chan, Packard, Thomas A., Vardi, Noam, Schwarzer, Roland, Gramatica, Andrea, Deeks, Steven G., Williams, Steven R., Landgraf, Kyle, Killeen, Nigel, Martin, David W., Weinberger, Leor S., Greene, Warner C.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922308/
https://ncbi.nlm.nih.gov/pubmed/31668804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.10.002
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