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Fast read alignment with incorporation of known genomic variants

BACKGROUND: Many genetic variants have been reported from sequencing projects due to decreasing experimental costs. Compared to the current typical paradigm, read mapping incorporating existing variants can improve the performance of subsequent analysis. This method is supposed to map sequencing rea...

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Détails bibliographiques
Publié dans:BMC Med Inform Decis Mak
Auteurs principaux: Guo, Hongzhe, Liu, Bo, Guan, Dengfeng, Fu, Yilei, Wang, Yadong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921400/
https://ncbi.nlm.nih.gov/pubmed/31856811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-019-0960-3
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