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Fast read alignment with incorporation of known genomic variants

BACKGROUND: Many genetic variants have been reported from sequencing projects due to decreasing experimental costs. Compared to the current typical paradigm, read mapping incorporating existing variants can improve the performance of subsequent analysis. This method is supposed to map sequencing rea...

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Библиографические подробности
Опубликовано в: :BMC Med Inform Decis Mak
Главные авторы: Guo, Hongzhe, Liu, Bo, Guan, Dengfeng, Fu, Yilei, Wang, Yadong
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921400/
https://ncbi.nlm.nih.gov/pubmed/31856811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-019-0960-3
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