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deSALT: fast and accurate long transcriptomic read alignment with de Bruijn graph-based index
The alignment of long-read RNA sequencing reads is non-trivial due to high sequencing errors and complicated gene structures. We propose deSALT, a tailored two-pass alignment approach, which constructs graph-based alignment skeletons to infer exons and uses them to generate spliced reference sequenc...
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| Publicado no: | Genome Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6913027/ https://ncbi.nlm.nih.gov/pubmed/31842925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1895-9 |
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