Short Read Alignment Based on Maximal Approximate Match Seeds

Sequence alignment is a critical step in many critical genomic studies, such as variant calling, quantitative transcriptome analysis (RNA-seq), and metagenomic sequence classification. However, the alignment performance is largely affected by repetitive sequences in the reference genome, which exten...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Quan, Wei, Guan, Dengfeng, Quan, Guangri, Liu, Bo, Wang, Yadong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674947/
https://ncbi.nlm.nih.gov/pubmed/33251246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.572934
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