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Replenishment of Hepatitis B Virus cccDNA Pool Is Restricted by Baseline Expression of Host Restriction Factors In Vitro

Background: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) is the major cause of viral persistence in patients with chronic HBV infection. Understanding the mechanisms underlying stability and persistence of HBV cccDNA in hepatocytes is critical for developing novel therapeutics...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Microorganisms
Κύριοι συγγραφείς: Brezgin, Sergey, Kostyusheva, Anastasiia, Bayurova, Ekaterina, Gordeychuk, Ilya, Isaguliants, Maria, Goptar, Irina, Nikiforova, Anastasiia, Smirnov, Valery, Volchkova, Elena, Glebe, Dieter, Kostyushev, Dmitry, Chulanov, Vladimir
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920784/
https://ncbi.nlm.nih.gov/pubmed/31698767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms7110533
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