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Lymphocyte-Activation Gene 3 (LAG3): the Next Immune Checkpoint Receptor
Immune checkpoint therapy has revolutionized cancer treatment by blocking inhibitory pathways in T cells that limits the an effective anti-tumor immune response. Therapeutics targeting CTLA-4 and PD1/PDL1 have progressed to first line therapy in multiple tumor types with some patients exhibiting tum...
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| Опубликовано в: : | Semin Immunol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920665/ https://ncbi.nlm.nih.gov/pubmed/31604537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2019.101305 |
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